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Buckthorn (californian)
Name :Buckthorn (californian)
Botanical :Rhamnus purshianus
Synonyms : Sacred Bark. Cascara Sagrada.
Family :Rhamnaceae
Parts Used :Bark.
Description :As imported, the drug mostly occurs in quills or incurved pieces of varying lengths and sizes, smooth or nearly so externally, covered with a greyish-white layer, which is usually easily removed, and frequently marked with spots or patches of adherent lichens. Beneath the surface it is violet-brown, reddish-brown or brownish, and internally a pale yellowish-brown and nearly smooth. It has no marked odour, but a nauseous, bitter taste.

It is frequently also imported in flattened packets, consisting of small pieces of the bark compressed into a more or less compact mass.

The fluid extract is made by maceration and percolation with diluted alcohol and evaporation.
Constituents :The chemical constituents of the bark are but imperfectly known. It has been proved to contain Emodin and an allied substance possibly identical with the Frangula-Emodin of Alder Buckthorn bark. Fat, starch, glucose, a volatile odorous oil, malic and tannic acids are also present. The assertion has been made that the bark contains glucosides which yield on hydrolysis Chrysophanic acid, but the evidence on this point is conflicting.
Uses :Cascara Sagrada is a mild laxative, acting principally on the large intestine. It is considered suitable for delicate and elderly persons, and may with advantage be given in chronic constipation, being generally administered in the form of the fluid extract.

It acts also as a stomachic tonic and bitter, in small doses, promoting gastric digestion and appetite.

 

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